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The project was significantly supported by the German Cancer Consortium (DKTK), the German Cancer Aid, the German Childhood Cancer Foundation, and the Federal Ministry of Education and Research (BMBF). Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort. Online publication 10th May 2018; DOI: A picture is available for download:https://de/de/presse/pressemitteilungen/2014/bilder/Picture Caption: MRT picture of a medulloblastoma Note on use of images related to press releases Use is free of charge.The German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) permits one-time use in the context of reporting about the topic covered in the press release.The staff of the Cancer Information Service (KID) offers information about the widespread disease of cancer for patients, their families, and the general public.Jointly with Heidelberg University Hospital, DKFZ has established the National Center for Tumor Diseases (NCT) Heidelberg, where promising approaches from cancer research are translated into the clinic.Medulloblastoma is a rare malignant tumor of the cerebellum and occurs predominantly in children.Scientists believe that in many cases hereditary gene defects trigger the development of this malignant disease.The results are particularly important because both, materials from previous studies and patient data from four current or recently completed clinical trials were included in the analysis.Based on these findings and other tumor features, the scientists developed criteria for routine genetic screening.

To make this possible, Stefan Pfister and Christian Kratz from the Hannover Medical School have created a registry for patients with a hereditary cancer predisposition and a website that contains information for patients, families, and physicians (At DKFZ, more than 1,000 scientists investigate how cancer develops, identify cancer risk factors and endeavor to find new strategies to prevent people from getting cancer.They develop novel approaches to make tumor diagnosis more precise and treatment of cancer patients more successful.Images have to be cited as follows: "Source: Wikimedia/Hellerhoff".Distribution of images to third parties is not permitted unless prior consent has been obtained from DKFZ's Press Office (phone: 49-(0)6221 42 2854, E-mail: [email protected]). The German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)The German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) with its more than 3,000 employees is the largest biomedical research institute in Germany.

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